Fatal cerebral oedema in adult diabetic ketoacidosis.
نویسندگان
چکیده
In this report, a case of adult onset fatal cerebral oedema as a rare complication of diabetic ketoacidosis (DKA) is described and confirmed at post-mortem pathological examination. The pathogenesis of cerebral oedema due to DKA is still unknown. Potential mechanisms include the administration of sodium bicarbonate leading to intracellular acidosis, excessive fluid infusion causing swelling of brain tissue, or reduction of plasma osmolarity by a rapid fall in glucose levels causing osmotic swelling.
منابع مشابه
Hypopituitarism following cerebral oedema with diabetic ketoacidosis.
Clinical evidence of cerebral oedema occurs in approximately 1% of diabetic ketoacidosis episodes. Mortality from this serious complication is falling, but little is known of long term outcome. We describe hypopituitarism and executive dysfunction developing two years after cerebral oedema complicating diabetic ketoacidosis in a 12 year old with type 1 diabetes.
متن کاملReversible cerebral oedema complicating diabetic ketoacidosis.
A young man with diabetic ketoacidosis developed the clinical features of cerebral oedema. This resolved without specific treatment. The mortality from ketoacidosis might be reduced if the syndrome was suspected and treated earlier.
متن کاملبررسی فاکتورهای مستعد کننده، عوارض و پیش آگهی در کودکان مبتلا به کتواسیدوز دیابتی در زنجان
Background and Objective: Diabetic ketoacidosis is one of the most common and life threatening complications in children with diabetes mellitus. The aim of this study was to evaluate predisposing factors, complications and prognosis of the patients with diabetic ketoacidosis admitted to Zanjan hospitals. Materials and Methods: The records of patients with DKA admitted to Mousavi and Vali-e Asr ...
متن کاملA Case of Recurrent Cerebral Oedema in Diabetic Ketoacidosis
A 7-year-old girl presented with new onset type 1 diabetes, with moderate diabetic ketoacidosis. She developed clinical and radiologically confirmed cerebral oedema managed with mannitol. Despite slow normalisation of biochemical parameters and marked clinical improvement, she had a further episode of symptomatic cerebral oedema 50 hours following presentation.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Netherlands journal of medicine
دوره 68 1 شماره
صفحات -
تاریخ انتشار 2010